For most people, the ResMed AirSense 11 AutoSet ($799–$819) is the better buy — it adds a touchscreen, Bluetooth, an AutoSet for Her mode, and a guided Personal Therapy Assistant over the older AirSense 10 AutoSet ($699–$719). But both deliver identical core therapy — AutoSet auto-adjusting pressure, integrated HumidAir humidification, and EPR comfort. If you'd rather save about $100 and don't need the newer interface, the AirSense 10 is still an excellent machine.
AirSense 11 vs. AirSense 10: full comparison
| Feature | AirSense 11 AutoSet | AirSense 10 AutoSet |
|---|---|---|
| Price | $799–$819 | $699–$719 |
| Display & controls | Color touchscreen | LCD screen with buttons |
| Therapy modes | AutoSet, AutoSet for Her, CPAP | AutoSet, CPAP |
| Connectivity | Cellular + Bluetooth (myAir app) | Cellular (myAir app) |
| Auto-adjusting pressure (AutoSet) | Yes | Yes |
| Integrated HumidAir humidifier | Yes | Yes |
| Expiratory Pressure Relief (EPR) | Yes | Yes |
| ClimateLineAir heated tubing compatible | Yes | Yes |
| Personal Therapy Assistant (guided setup) | Yes | No |
| Maintenance reminders | Automated | Manual |
| Optional battery backup | Yes | Yes (external) |
| FAA-approved for travel | Yes | Yes |
| Mask compatibility | Most ResMed & other brands | Most ResMed & other brands |
What's the same between the AirSense 11 and 10?
This is the key point most comparisons miss: the two machines deliver the same core therapy. Both use ResMed's AutoSet algorithm to auto-adjust pressure through the night, both have an integrated HumidAir heated humidifier, both offer Expiratory Pressure Relief (EPR) for easier exhalation, both work with ClimateLineAir heated tubing, and both are FAA-approved and compatible with most ResMed and third-party masks. Clinically, you're getting equivalent treatment from either machine.
What the AirSense 11 adds over the AirSense 10
The upgrades are about convenience and experience, not therapy quality:
- Touchscreen interface: the AirSense 11 replaces the AirSense 10's button-and-dial controls with a color touchscreen that's easier to navigate.
- Bluetooth: the AirSense 11 adds Bluetooth on top of cellular connectivity, making setup and phone pairing simpler.
- AutoSet for Her mode: a therapy mode tuned to patterns more common in female users.
- Personal Therapy Assistant: guided video tutorials and troubleshooting through the myAir app — helpful for first-time users.
- Automated maintenance reminders: the machine prompts you when it's time to replace filters and parts.
Which one should you buy?
Choose the AirSense 11 if you're new to CPAP and want the easiest setup experience, you prefer a touchscreen, you want Bluetooth pairing, or the AutoSet for Her mode applies to you. It's the current flagship and our most popular machine.
Choose the AirSense 10 if you want to save about $100, you're comfortable with simple button controls, or you're replacing an older AirSense 10 and want to keep the same familiar interface and accessories. The core therapy is identical.
Either way, a certified refurbished version can lower the cost further — a refurbished AirSense 11 starts at $449.
The bottom line
The AirSense 11 is the better all-around machine thanks to its touchscreen, Bluetooth, and guided setup — but the AirSense 10 delivers the exact same therapy for about $100 less, which makes it a smart budget pick. Compare both in our best CPAP machines guide, or shop the full auto CPAP lineup.