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Key Features

  1. AutoSet Technology: Advanced AutoSet algorithm adjusts therapy pressure on a breath-by-breath basis to provide optimal therapy comfort and effectiveness.
  2. Integrated Humidifier (HumidAir): Built-in humidification system adds moisture to the air, reducing dryness and irritation during therapy.
  3. Slimline Tubing: The slimline tubing is designed to be lightweight and flexible, providing ease of use and minimizing drag during sleep.
  4. User-Friendly Interface: Intuitive and user-friendly interface with a color display for easy navigation and adjustment of settings.
  5. Quiet Operation: Designed for quiet operation to minimize disruptions for the user and their sleep partner.
  6. SmartStart and SmartStop: SmartStart feature begins therapy as soon as the user breathes into the mask, and SmartStop stops therapy when the mask is removed.
  7. Expiratory Pressure Relief (EPR): EPR feature lowers pressure during exhalation to enhance comfort.
  8. AutoRamp Technology: Gradual pressure ramp-up at the beginning of the therapy session for a more comfortable start.
  9. Climate Control: Advanced climate control features aim to maintain optimal conditions, adjusting to changes in room temperature and humidity.
  • Description
  • Parts
  • Specs
  • Included Items
  • Reviews 36
  • Q&A

The ResMed AirSense 11 AutoSet CPAP machine is a groundbreaking advancement in sleep apnea therapy, offering unparalleled comfort, user-friendly features, and efficient treatment. This auto CPAP device comes equipped with the integrated HumidAir humidifier and SlimLine tubing, ensuring optimal humidity control and enhanced comfort during therapy. As the latest innovation in CPAP technology, the AirSense 11 AutoSet is your ultimate partner for achieving restful sleep.

Comparison between ResMed SlimLine Tubing and ClimateLine Tubing

Feature SlimLine™ Tubing ClimateLine™ Tubing
Diameter 15mm, thinner and less bulky than standard tubing Standard diameter, 19mm
Flexibility and Drag Highly flexible with less drag, making it easier to manage and less intrusive during sleep Flexible but slightly stiffer compared to SlimLine™, designed to accommodate the heating element
Temperature Control No heating element, standard air delivery Integrated heating coil to maintain air temperature, preventing cool air from causing discomfort
Humidity Control Does not actively control humidity, works well with standard CPAP humidifier settings Actively manages humidity by maintaining warm air, works in conjunction with the machine’s humidifier to optimize moisture levels and reduce dryness
Compatibility Compatible with a broad range of ResMed machines, including the AirSense™ 11 and S9 series Specifically designed for use with ResMed’s AirSense™ 10 and 11 models that support Climate Control technology
Usage Ideal for users who value lightweight and less intrusive tubing, particularly favored among travelers Perfect for users in varied climates or those susceptible to nasal dryness and rainout; essential for maintaining consistent therapy conditions
Condensation Reduction Potential for condensation in cooler environments without active heating Significantly reduces condensation by actively heating the air, providing more stable therapy conditions throughout the night
Comfort Lightweight material and flexibility contribute to a comfortable fit, taking up less space and reducing the burden during sleep Enhanced comfort through temperature and humidity regulation, ensuring that air delivered feels natural and comfortable, especially in colder settings
Maintenance Simple to maintain, washable, and durable; no electronic components mean less hassle in care Requires careful maintenance to ensure the heating element functions properly; slightly more complex due to electronic components
Weight Lighter, creating less pull on the mask and allowing for greater freedom of movement Slightly heavier due to the heating elements but provides a more controlled therapy experience

Key Features of the AirSense 11 AutoSet CPAP Machine

  1. Advanced Auto CPAP Technology: The AirSense 11 AutoSet CPAP Machine automatically adjusts pressure levels to accommodate your specific breathing needs throughout the night, ensuring optimal therapy without the need for manual adjustments.
  2. Integrated HumidAir Humidifier: The AirSense 11 humidifier provides consistent humidification with adjustable settings, enhancing comfort by adding moisture to the air you breathe. This feature helps alleviate dryness in the nose, mouth, and throat for a more refreshing therapy experience.
  3. SlimLine Tubing: The lightweight, compact, and flexible SlimLine tubing minimizes drag and reduces the likelihood of tube entanglements during sleep. This design helps maintain moisture levels in the air you breathe, reducing common CPAP therapy side effects.
  4. Touchscreen Interface and MyAir Compatibility: The modern touchscreen interface makes navigation and settings adjustment intuitive and straightforward. Paired with ResMed's MyAir app, users can easily track their sleep therapy progress and manage machine settings from their mobile devices.
  5. Heated Tubing Options: The AirSense 11 can be used with ClimateLineAir heated tubing, further enhancing humidity control and preventing condensation within the tube for a more comfortable therapy experience.
  6. Expiratory Pressure Relief (EPR): The EPR feature reduces pressure as you exhale, making it easier to breathe out against the incoming air and enhancing overall comfort.
  7. Included Filter: The machine includes a fine mesh disposable air filter that helps filter out environmental particulates, ensuring clean air and protecting the machine motor from dust build-up.

Benefits of Using the ResMed AirSense 11 Auto CPAP Machine

  1. Optimal Humidity and Comfort: The integrated HumidAir humidifier and optional ClimateLineAir tubing provide a controlled therapeutic environment, reducing common issues like rainout or dry mouth and enhancing therapy comfort.
  2. User-Friendly Design: From easy-to-use touchscreen controls to simple setup and operation, every aspect of the AirSense 11 is designed to make sleep apnea therapy hassle-free.
  3. Enhanced Sleep Tracking and Data Management: The AirSense 11 collects therapy data and provides actionable insights through the MyAir app, allowing users and healthcare providers to monitor therapy effectiveness and make timely adjustments.
  4. Travel-Friendly Features: The compact and lightweight design, along with a travel bag, makes it easy to take your CPAP therapy wherever you go. The AirSense 11 also includes an in-flight mode for convenience during air travel.

Important Note: Always check with your airline regarding their on-board CPAP use policy before traveling.

ResMed AirSense 11 AutoSet CPAP is Ideal For

The ResMed AirSense 11 AutoSet CPAP Machine is an ideal solution for a wide range of individuals seeking effective and comfortable sleep apnea therapy. Here’s why this machine stands out as an optimal choice for various users:

1. Individuals with Obstructive Sleep Apnea (OSA)

The AirSense 11 is specifically designed for those suffering from obstructive sleep apnea. Its auto-adjusting technology efficiently manages and adapts pressure levels throughout the night to accommodate changes in breathing patterns. This feature ensures continuous, effective treatment of apnea events, making it ideal for those needing reliable management of their sleep apnea.

2. Users Looking for Enhanced Comfort

With its integrated HumidAir humidifier and optional ClimateLineAir heated tubing, the AirSense 11 provides personalized climate control, significantly enhancing comfort. This is especially beneficial for users who experience dryness or irritation from CPAP therapy. The machine’s ability to adjust humidity and temperature settings helps minimize these discomforts, providing a more pleasant and tolerable therapy experience.

3. Technology-Savvy Individuals

The AirSense 11 boasts advanced features like intuitive touchscreen controls and seamless connectivity with the MyAir app. For users who appreciate technology and want to actively engage with their therapy management, this machine offers detailed sleep tracking, feedback, and the ability to adjust settings remotely. This makes it ideal for those who prefer a hands-on approach to their health management.

4. Frequent Travelers

This CPAP machine is also perfect for individuals who travel often. Its compact design, universal power supply, and FAA compliance for in-flight use make it easy to carry and use on the go. The inclusion of a travel bag further enhances its portability, ensuring that users can continue their therapy seamlessly while traveling.

5. Patients Needing Reliable Leak Management

Equipped with advanced leak detection technology, the AirSense 11 is suitable for patients concerned about the efficacy of their therapy due to mask leaks. The machine's algorithms continuously monitor and compensate for leaks, ensuring that the therapy remains effective and uninterrupted, thereby maximizing the therapeutic benefits.

6. New CPAP Users

For individuals new to CPAP therapy, the AirSense 11 offers an unintimidating, user-friendly introduction. Its easy setup, simple maintenance, and automatic adjustments provide a stress-free experience, helping new users adapt to CPAP therapy smoothly and effectively.

Setting up AirSense 11 AutoSet CPAP With HumidAir and SlimLine Tube for the First Time

Setting up your new ResMed AirSense 11 AutoSet CPAP machine for the first time can be an exciting step towards better sleep health. Here’s a detailed guide on how to properly assemble and configure your machine to ensure optimal performance right from the start.

1. Unboxing Your Device

First, carefully unpack your AirSense 11 AutoSet CPAP machine. Inside the box, you should find:

  • The AirSense 11 AutoSet machine
  • HumidAir humidifier built into the device
  • SlimLine tubing
  • Power supply and cord
  • A disposable filter already installed
  • User manual and other documentation

2. Connecting the Components

  1. Attach the SlimLine Tube: Connect one end of the SlimLine tubing to the air outlet located on the back of the machine. The tubing is lightweight and designed to reduce bulk and minimize pull on the mask during movement. You can also use AirSense 11 ClimateLineAir Heated Tubing (Optional) - This is a heated tubing that helps reduce CPAP side effects like rainout or dry mouth.

  2. Prepare the HumidAir Humidifier:

  • Open the humidifier by pressing the release latch on the top of the water chamber.
  • Fill the water chamber with distilled water up to the maximum fill line. Do not overfill as this could lead to water entering the machine and causing damage.
  • Carefully close the lid ensuring it snaps into place, ensuring a secure and leak-free seal.

3. Powering Up the Machine

  1. Connect the Power Supply: Insert one end of the power cord into the machine and the other end into a power outlet. It’s advisable to plug the device directly into a wall outlet rather than using an extension cord to avoid any potential power issues.

  2. Turn On the Machine: Press the power button located on the top of the device. Upon first startup, the AirSense 11 will display a welcome message on its color LCD touchscreen.

4. Configuring Initial Settings

  1. Set the Time and Date: Follow the on-screen prompts to adjust the time and date. This information is crucial for accurately logging your therapy data.

  2. Adjust Comfort Settings: Navigate through the menu to set features like humidity level, tube temperature (if using heated tubing), and Expiratory Pressure Relief (EPR) to enhance comfort. These settings can be adjusted to match your personal preference or based on the advice of your healthcare provider.

  3. Connect to MyAir: Set up connectivity with ResMed’s MyAir app by following the on-screen instructions. This will allow you to track your therapy progress and receive tips and support directly on your smartphone.

5. Testing the Device

Before going to sleep, it’s a good idea to test the machine:

  • Wear your CPAP mask and connect it to the free end of the SlimLine tubing.
  • Lay down in your typical sleeping position.
  • Start the therapy by using the 'Start' function on the device or by breathing into the mask if the SmartStart feature is activated.
  • Ensure that air is flowing comfortably and that there are no significant air leaks around the mask.

6. Safety Checks

  • Ensure that all connections are secure to prevent air leaks.
  • Verify that the humidifier water chamber is correctly assembled to avoid any water leakage into the machine.

By following these steps, your AirSense 11 AutoSet CPAP machine with HumidAir and SlimLine tubing will be optimally set up to provide you with reliable and comfortable therapy from the very first use. This initial setup process is crucial for ensuring that the machine operates effectively and safely, helping you to achieve the best possible results in managing your sleep apnea.

Cleaning Your CPAP Hose

  1. Flush the hose with a solution of mild soap mixed with water to cleanse it.
  2. Employ a tube brush to thoroughly scrub the interior of the hose, eliminating any accumulated debris or bacteria.
  3. Rinse the hose thoroughly with clean water to ensure all soap residue is removed.
  4. Drape the hose over a towel rack to air dry.

Maintenance Tips for Humidifier

  • Avoid overfilling the water chamber beyond the maximum fill line to prevent water from leaking into and potentially damaging your machine.
  • After use, let the water chamber stand for ten minutes to cool down before handling it, as it may be hot.

Replacement Schedules

Maintaining the ResMed AirSense 11 AutoSet CPAP machine involves regular replacements of various components to ensure optimal performance and hygiene. Here’s a detailed guide on the recommended replacement schedules for different parts of the machine:

1. Air Filters

Replacement Schedule: Every month The disposable fine mesh air filters play a crucial role in ensuring clean air flows through the machine. These should be checked monthly and replaced if they appear dirty or discolored. Regular replacement helps maintain air quality and protects the machine's internal components.

2. Humidifier Water Chamber

Replacement Schedule: Every 6 months Replace the water chamber semi-annually to prevent bacterial growth and mineral buildup, which can affect the machine's performance and the quality of humidification. Regular inspections for signs of wear or damage are also advisable.

3. CPAP Mask Components

  • Cushions and Nasal Pillows: Every month
  • Headgear and Frames: Every 3 to 6 months

The parts of the mask that contact the face, like cushions and nasal pillows, should be replaced monthly to ensure a good seal and comfortable fit. Over time, these components can lose their shape and elasticity, leading to air leaks and reduced effectiveness of the therapy. Headgear and mask frames typically have a longer life but should be checked regularly for elasticity and replaced as needed to ensure a proper fit.

4. CPAP Tubing

Replacement Schedule: Every 3 months The tubing should be replaced quarterly to ensure it remains free of any holes, tears, or significant wear that could compromise the delivery of air pressure. Regular replacement also reduces the risk of contaminant buildup inside the tube.

5. Non-Disposable Filters (if applicable)

Replacement Schedule: Every 6 months If your machine uses a non-disposable, or washable, filter, it should be cleaned monthly and replaced every six months. These filters require regular maintenance to continue effectively filtering out dust and particulate matter.

When looking to buy the ResMed AirSense 11, consider the AirSense 11 humidifier and AirSense 11 tubing as essential components for a comfortable and effective therapy experience. The ResMed AirSense 11 humidity control and AirSense 11 hose contribute to the overall comfort and effectiveness of the therapy, making it an excellent choice compared to the ResMed AirSense 10. Experience the difference with the ResMed AirSense 11 AutoSet and enjoy a better night's sleep.

Comparing Similar Products

If you're considering the Resmed AirSense 10 AutoSet (AirSense 10) or other CPAP machines, the AirSense 11 offers a significant leap forward. The AirSense 11 boasts improved algorithms, quieter operation, and a more user-friendly interface with a touchscreen display, compared to the knob-based controls of older models.


Related parts
Manufacturer ResMed
Warranty 2-Year Manufacturer Warranty
Color Black, White
Sound Level 27 dB
Auto Start/Stop Yes
Filters Replaceable Filters
Machine Weight 2.5 lb (1.13 kg)
Machine Size Only 10.21" x 3.72" x 5.45" in
Machine Size with Humidifier 9.32" x 3.72" x 5.45" in
Humidification System Built-in heated humidifier (HumidAir Integrated Humidifier in Input 2)
Integrated Heated Hose Yes
Humidifier Settings 0-8 (Auto, Manual with humidity levels 1-8 in Input 2)
Water Chamber Capacity 380 mL
AC Input 100-240V, 50-60Hz
AC Power Supply 65W
Power Cord Length 1.8 m (6 ft)
Battery Option No
Bluetooth Yes
Remote Monitoring Yes, built-in cellular modem
Data Download Yes, via SD card or Bluetooth
Pressure Range 4-20 cm H2O
Pressure Relief EPR 1 to 3
Starting Ramp Pressure 4 cm H2O default
AHI Display Machine, App
FAA Approved Yes
Oxygen Use Yes up to 15L/min
Heated No
Reduces Condensation No
Maintains Air Temperature No
  • ResMed AirSense 11 AutoSet with built-in heated humidifier
  • New humidifier water chamber tub
  • Standard SlimLine Tubing
  • Power Supply
  • Travel Carry Bag
  • SD Card

Compare with similar products

Basic Features
2-Year Manufacturer Warranty
2-Year Manufacturer Warranty
2 Year Manufacturer Warranty
Black, White
Black, White
Sound Level
27 dB
27 dBA
26.6 dBA
Auto Start/Stop
Yes (SmartStart™ Feature)
Replaceable Filters
Replaceable Filters
Disposable filter (1 included)
Machine Weight
2.5 lb (1.13 kg)
2.5 lb (1.13 kg)
2.45 lb
Machine Size Only
10.21" x 3.72" x 5.45" in
10.21" x 3.72" x 5.45" in
8" x 4.6" x 5.91" in
Machine Size with Humidifier
9.32" x 3.72" x 5.45" in
9.32" x 3.72" x 5.45" in
10" x 4.6" x 5.91" in
Humidifier Features
Humidification System
Built-in heated humidifier (HumidAir Integrated Humidifier in Input 2)
Built-in heated humidifier (HumidAir Integrated Humidifier in Input 2)
Built-in heated humidifier
Integrated Heated Hose
Humidifier Settings
0-8 (Auto, Manual with humidity levels 1-8 in Input 2)
0-8 (Auto, Manual with humidity levels 1-8 in Input 2)
Auto, Manual (Humidity Levels 1-8)
Water Chamber Capacity
380 mL
380 mL
380 mL
Power Features
AC Input
100-240V, 50-60Hz
100-240V, 50-60Hz
100-240V, 50-60Hz
AC Power Supply
Power Cord Length
1.8 m (6 ft)
6 ft
1.8 m (6 ft)
Battery Option
Operating Modes
AutoSet/APAP, AutoSet/APAP For Her, CPAP
AutoSet/APAP, AutoSet/APAP For Her, CPAP
Altitude Adjustment
Automatic up to 9,870 feet
Automatic up to 9,870 feet
Automatic up to 8500 feet
Software Features
Remote Monitoring
Yes, built-in cellular modem
Yes, built-in cellular modem
Data Download
Yes, via SD card or Bluetooth
Yes, via SD card or Bluetooth
Yes via SD card
Pressure Features
Pressure Range
4-20 cm H2O
4-20 cm H2O
4 to 20 cm H2O
Pressure Relief
EPR 1 to 3
EPR 1 to 3
EPR 1 to 3 (1 is min pressure relief, 3 is max)
Starting Ramp Pressure
4 cm H2O default
4 cm H2O default
4 cm H2O default
Additional Features
AHI Display
Machine, App
Machine, App
Machine, app
FAA Approved
Oxygen Use
Yes up to 15L/min
Yes up to 15L/min
Yes, up to 4L/min
Oximetry Compatibility
Yes, ResMed AirSense/AirCurve 10 Oximetry Kit (370004)
Yes, ResMed AirSense/AirCurve 10 Oximetry Kit (370004)
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What is the ResMed 39000 AirSense 11 AutoSet CPAP with HumidAir & Slimline Tube?
The ResMed AirSense 11 AutoSet CPAP Machine is an advanced auto-adjusting device designed to enhance your sleep therapy by automatically adjusting pressure levels to suit your breathing needs. It's engineered for users with sleep apnea who need a reliable, smart, and user-friendly device to maintain open airways throughout the night.
What are the benefits of using the ResMed AirSense 11 AutoSet CPAP Machine?
  • Improved Sleep Quality: By providing consistently optimized air pressure and making breathing easier during sleep, the AirSense 11 helps users achieve deeper and more restorative sleep. 
  • Enhanced Comfort: The humidification and heated tubing options, along with pressure relief features, make therapy more comfortable, encouraging higher compliance rates. 
  • Convenient Monitoring and Adjustment: With the integrated touchscreen and wireless connectivity to the myAir app, users can easily monitor their therapy and make adjustments as needed without the need for professional assistance. 
  • Versatile and User-Friendly: Designed to be intuitive and easy to use, the AirSense 11 caters to both new and experienced CPAP users, simplifying the therapy process and enhancing overall user satisfaction.
What are the key features of the ResMed AirSense 11 AutoSet CPAP Machine?
  • Auto-Adjusting Pressure: Automatically adapts to the user’s breathing pattern to provide the optimal pressure at all times. 
  • Integrated HumidAir Humidifier: Offers built-in humidification for added comfort during therapy, which can be customized according to personal preference. 
  • Color Touchscreen Interface: Simplifies the navigation and customization of settings, making the machine more intuitive and user-friendly. 
  • Wireless Connectivity: Compatible with the ResMed MyAir app, allowing users to track and manage their therapy and receive personalized insights and coaching. 
  • Expiratory Pressure Relief (EPR): Reduces pressure upon exhalation to make breathing more comfortable while maintaining effective therapy.
How do I clean and maintain the AirSense 11 AutoSet CPAP with HumidAir & Slimline Tube?
It is essential to regularly clean the mask, tubing, humidifier chamber, and filters of the device to maintain hygiene and performance. Follow the manufacturer's instructions for proper cleaning and maintenance procedures.
Can the AirSense 11 AutoSet CPAP be connected to a mobile app for data tracking?
Yes, the AirSense 11 AutoSet CPAP is compatible with ResMed's MyAir mobile app, allowing users to track their therapy data, receive feedback, and monitor their progress over time.
Is the AirSense 11 AutoSet CPAP suitable for travel?
The compact design of the AirSense 11 AutoSet CPAP, along with its travel-friendly features, makes it suitable for travel. Ensure to check airline regulations and use a carrying case for easy transportation.
How can I adjust the settings on the AirSense 11 AutoSet CPAP?
The AirSense 11 AutoSet CPAP allows users to adjust various settings such as humidity levels, ramp time, and mask fit using the device's intuitive menu interface. Refer to the user manual for detailed instructions on adjusting settings.
How does the AutoRamp feature on the AirSense 11 AutoSet CPAP benefit users?
The AutoRamp feature detects when a user falls asleep and automatically starts the pressure at a lower level, gradually increasing to the prescribed pressure to enhance comfort and ease the transition into therapy.
Can the AirSense 11 AutoSet CPAP with HumidAir & Slimline Tube be used with different types of masks?
Yes, the AirSense 11 AutoSet CPAP is compatible with a variety of CPAP masks, including nasal masks, nasal pillows, and full-face masks, offering users flexibility to choose a mask that suits their comfort and therapy needs.
How often should the filters in the AirSense 11 AutoSet CPAP be replaced?
It is recommended to regularly check and replace the filters in the AirSense 11 AutoSet CPAP based on the manufacturer's guidelines to maintain optimal air quality and device performance.
How does the Expiratory Pressure Relief (EPR) feature work on the AirSense 11 AutoSet CPAP?
The EPR feature reduces the pressure during exhalation, making it easier for users to breathe out against the pressure from the CPAP device, enhancing comfort and compliance during therapy.
What accessories are included with the ResMed AirSense 11 AutoSet CPAP Machine?
The standard package typically includes the CPAP machine with an integrated HumidAir humidifier, a power supply, a power cord, a disposable air filter, and SlimLine tubing. A travel bag and user manual are also included to facilitate portability and ease of use.
Does the ResMed AirSense 11 AutoSet CPAP Machine come with a SlimLine tubing?
Yes, the ResMed AirSense 11 typically includes SlimLine tubing, which is lightweight and flexible, designed to reduce drag and pull on the mask to help maintain a comfortable seal during movement.
Can the ResMed AirSense 11 AutoSet CPAP Machine be used with a ClimateLine or ClimateLineAir heated tube?
Yes, the AirSense 11 can be used with an optional ClimateLineAir heated tubing to further enhance comfort. This tubing helps maintain the temperature and humidity levels of the air delivered to the user, reducing common issues such as dryness and rainout.